Right back Jesus Sanchez and winger Javier Lopez will miss out on Wednesday's contest.
Injuries to most of the back line have struck Chivas this season, while Angel Zaldivar's absence has forced Almeyda to turn to players like teenager Jose Juan Macias or 20-year-old Jesus Godinez to spell Alan Pulido. His team isn't deep enough for a six-match run at the trophy, especially with the second tiebreaker in the quarterfinal and semifinal going to the team with a better regular-season finish.